論文・著書

Tsuji M, OhshimaM, Yamamoto Y, Saito S, Hattori Y, Tanaka E, Taguchi A, Ihara M, Ogawa Y. Cilostazol, a phosphodiesterase 3 inhibitor, moderately attenuates behaviors depending on sex in the Ts65Dn mouse model of Down syndrome. Front Aging Neurosci 12:106 (2020)

Tsuji M, Sawada M, Watabe S, Sano H, Kanai M, Tanaka E, Ohnishi S, Sato Y, Sobajima H, Hamazaki T, Mori R, Oka A, Ichiba H, Hayakawa M, Kusuda S, Tamura M, Nabetani M, Shintaku H. Autologous cord blood cell therapy for neonatal hypoxic-ischaemic encephalopathy: a pilot study for feasibility and safety. Sci Rep 10:4603 (2020)

Ohki A, Saito S, Hirayama E, Takahashi Y, Ogawa Y, Tsuji M, Higuchi T, Fukuchi K. Comparison of chemical exchange saturation transfer imaging with diffusion-weighted imaging and magnetic resonance spectroscopy in a rat model of hypoxic-ischemic encephalopathy. Magn Reson Med Sci (in press)

Kitase Y, Sato Y, Ueda K, Suzuki T, Mikrogeorgiou A, Sugiyama Y, Matsubara K, Tsukagoshi Okabe Y, Shimizu S, Hirata H, Yukawa H, Baba Y, Tsuji M, Takahashi Y, Yamamoto A, Hayakawa M. A novel treatment with stem cells from human exfoliated deciduous teeth for hypoxic-ischemic encephalopathy in neonatal rats. Stem Cell Dev 29:63-74 (2020)

Coq JO, KochmannM, Lacerda DC, Khalki H, Delcour M, Toscano AE, Cayetanot F, Canu MH, Barbe MF, Tsuji M. From cerebral palsy to developmental coordination disorder: Development of preclinical rat models corresponding to recent epidemiological changes. Ann Phys Rehabil Med 19:30161-30167 (2019)

Tsuji M, Sizonenko SV, Baud O. Editorial: Preventing developmental brain injury – from animal models to clinical trials. Front Neurol 10:775 (2019)

TsujiM. Hematopoietic stem cells for perinatal brain injury. In: Shinataku H ed. Cell Therapy for Perinatal Brain Injury. P45-56. Springer Nature Singapore Pte Ltd. (2018)

TsujiM, Shintaku H. Clinical trial of autologous cord blood cell therapy for neonatal hypoxic-ischemic encephalopathy (HIE). In: Shinataku H ed. Cell Therapy for Perinatal Brain Injury. P1-15. Springer Nature Singapore Pte Ltd. (2018)

Sugiyama Y, Sato Y, Kitase Y, Suzuki T, Kondo T, Mikrogeorgiou A, Horinouchi A, Maruyama S, Shimoyama Y, Tsuji M, Suzuki S, Yamamoto T, Hayakawa M. Intravenous administration of bone marrow-derived mesenchymal stem cell, but not adipose tissue-derived stem cell, ameliorated the neonatal hypoxic-ischemic brain injury by changing cerebral inflammatory state in rat. Front Neurol 9:757 (2018)

Sato Y, Ueda K, Kondo T, Hattori T, Mikrogeorgiou A, Sugiyama Y, Suzuki T, Yamamoto M, Hirata H, Hirakawa A, Nakanishi K, Tsuji M, Hayakawa M. Administration of Bone Marrow-Derived Mononuclear Cells Contributed to the Reduction of Hypoxic-Ischemic Brain Injury in Neonatal Rats. Front Neurol 9:987 (2018)

Coq JO, Delcour M, Ogawa Y, Peyronnet J, Castets F, Turle-Lorenzo N, Montel V, Bodineau L, Cardot P, Brocard C, Liabeuf S, Bastide B, Canu MH, Tsuji M, Cayetanot F. Mild intrauterine hypoperfusion leads to lumbar and cortical hyperexcitability, spasticity and muscle dysfunctions in rats: implications for prematurity. Front Neurol 9:423 (2018)

Ogawa Y, Tsuji M, Tanaka E, Miyazato M, Hino J. Bone morphogenetic protein (BMP)-3b gene depletion causes high mortality in a mouse model of neonatal hypoxic-ischemic encephalopathy.Front Neurol 9:397 (2018)

Tanaka E, Ogawa Y, Mukai T, Sato Y, Hamazaki T, Nagamura-Inoue T, Harada-Shiba M, Shintaku H, Tsuji M. Dose-Dependent effect of intravenous administration of human umbilical cord-derived mesenchymal stem cells in neonatal stroke mice. Front Neurol 9:133 (2018)

Tsuji M, Coq JO, Ogawa Y, Yamamoto Y, Ohshima M. A rat model of mild intrauterine hypoperfusion with microcoil stenosis. J Vis Exp 131: e56723 (2018)

Yasuno F, Kazui H, Kajimoto K, Ihara M, Morita N, Taguchi A, Yamamoto A, Matsuoka K, Takahashi M, Nakagawara J, Tsuji M, Iida H, Kishimoto T, Nagatsuka K. Mutual effect of cerebral amyloid-β and peripheral lymphocytes in cognitively normal elderly individuals. Int J Geriatric Psychiatry 32: e93-e99 (2017)

Mikrogeorgiou A, Sato Y, Kondo T, Hattori T, Sugiyama Y, Ito M, Saito A, Nakanishi K, Tsuji M, Kazama T, Kano K, Matsumoto T, Hayakawa M. Dedifferentiated fat cells, as a novel source for cell therapy to target neonatal hypoxic ischemic encephalopathy. Dev Neurosci 39: 273-286 (2017)

OhshimaM, Taguchi A, Sato Y, Ogawa Y, SaitoS, Yamahara K, Ihara M, Harada-Shiba M, Ikeda T, Matsuyama T, Tsuji M. Evaluations of intravenous administration of CD34+human umbilical cord blood cells in a mouse model of neonatal hypoxic-ischemic encephalopathy. Dev Neurosci 38: 331-341 (2016)

Ohshima M, Coq JO, Otani K, Hattori Y, Ogawa Y, Sato Y, Harada-Shiba M, Ihara M, Tsuji M. Mild intrauterine hypoperfusion reproduces neurodevelopmental disorders observed in prematurity. Sci Rep 6:39377 (2016)

Hattori Y, Enmi J, Iguchi S, Saito S, Yamamoto Y, Tsuji M, Nagatsuka K, Kalaria RN, Iida H, Ihara M. Gradual carotid artery stenosis in mice closely replicates hypoperfusive vascular dementia in humans. J Am Heart Assoc 4:e002022 (2016)

Hattori Y, Enmi J, Kitamura A, Yamamoto Y, Saito S, Takahashi Y, Iguchi S, Tsuji M, Yamahara K, Nagatsuka K, Iida H, Ihara M. A novel mouse model of subcortical infarcts with dementia. J Neurosci 35: 3915-3928 (2015)

Tsuji M, Johnston MV. Cell-based therapies in neonatal stroke. p321-349. In: Hess DC ed.Cell Therapy for Brain Injury.Springer International Publishing, Switzerland (2015)

Hattori T, Sato Y, Kondo T, Ichinohashi Y, Sugiyama Y, Yamamoto M, Kotani T, Hirata H, Hirakawa A, Suzuki S, Tsuji M, Ikeda T, Nakanishi K, Kojima S, Blomgren K, Hayakawa M. Administration of umbilical cord blood cells decreases hypoxic–ischemic brain injury in neonatal rats. Dev Neurosci 37: 95-104 (2015)

Ohshima M, Taguchi A, Tsuda H, Sato Y, Yamahara K, Harada-Shiba M, Miyazato M, Ikeda T, Iida H, Tsuji M. Intraperitoneal and intravenous deliveries are not comparable in terms of drug efficacy and cell distribution in neonatal mice with hypoxia-ischemia. Brain Dev 37: 376-386 (2015)

Hattori Y, Kitamura A, Tsuji M, Nagatsuka K, Ihara M. Motor and cognitive impairment in a mouse model of ischemic carotid artery disease. Neurosci Lett 581: 1-6 (2014)

Tsuji M, Taguchi A, Ohshima M, Kasahara Y, Sato Y, Tsuda H, Otani K, Yamahara K, Ihara M, Harada-Shiba M, Ikeda T, Matsuyama T. Effects of intravenous administration of umbilical cord blood CD34+cells in a mouse model of neonatal stroke. Neuroscience 263: 148-158 (2014)

Ihara M, Nishino M, Taguchi A, Yamamoto Y, Hattori Y, Saito S, Takahashi Y, Tsuji M, Kasahara Y, Takata Y, Okada M. Cilostazol add-on therapy in patients with mild dementia receiving donepezil: a retrospective study. PLoS One 9: e89516 (2014)

Taguchi A, Takata Y, Ihara M, Kasahara Y, Tsuji M, Nishino M, Stern D, Okada M. Cilostazol improves cognitive function in patients with mild cognitive impairment: a retrospective analysis. Psychogeriatrics 13: 164–169 (2013)

Tsuji M, Ohshima M, Taguchi A, Kasahara Y, Ikeda T, Matsuyama T. A novel reproducible model of neonatal stroke in mice: comparison with a hypoxia-ischemia model. Exp Neurol 247: 218-225 (2013)

Ohshima M, Tsuji M, Taguchi A, Kasahara Y, Ikeda T. Cerebral blood flow during reperfusion predicts later brain damage in a mouse and a rat model of neonatal hypoxic-ischemic encephalopathy. Exp Neurol 233: 481-489 (2012)

Tsuji M, Taguchi A, Ohshima M, Kasahara Y, Ikeda T. Progesterone and allopregnanolone exacerbate hypoxic-ischemic brain injury in immature rats. Exp Neurol 233: 214-220 (2012)

Tsuji M, Tamura T, Yoshida T, Haruta T. Multiple brainstem infarctions in a boy caused by angiitis of the basilar artery. Arch Dis Child 96: 195-196 (2011)

Kasahara Y, Tsuji M, Taguchi A. Umbilical cord blood and cell-based therapy for neurological diseases. In: Advances in Medicine and Biology. vol.26. p221-7. Nova Science Publishers, Inc. (2011)

Yagi M, Lee T, Awano H, Tsuji M, Tajima G, Kobayashi H, Hasegawa Y, Yamaguchi S, Takeshima Y, Matsuo M. A patient with mitochondrial trifunctional protein deficiency due to the mutations in the HADHB gene showed recurrent myalgia since early childhood and was diagnosed in adolescence. Mol Genet Metab 104: 556-559 (2011)

Tsuda H, Yamahara K, Ishikane S, Otani K, Nakamura A, Sawai K, Ichimaru N, Sada M, Taguchi A, Hosoda H, Tsuji M, Kawachi H, Horio M, Isaka Y, Kangawa K, Takahara S, Ikeda T. Allogenic fetal membrane-derived mesenchymal stem cells contribute to renal repair in experimental glomerulonephritis. Am J Physiol Renal Physiol 299: F1004-1013 (2010)

Tsuji M, Aoo N, Harada K, Sakamoto Y, Akitake Y, Irie K, Mishima K, Ikeda T, Fujiwara M. Sex differences in the benefits of rehabilitative training during adolescence following neonatal hypoxia-ischemia in rats. Exp Neurol 226: 285-292 (2010)

Tsuji M, Harada S, Ueno Y, Osaka N. Familial spinal neurofibromatosis: three generations of identical level symptomatic tumors. J Neurol Neurosurg Psychiatry 81: 1382 (2010)

Tsuji M, Yoshida T, Miyakoshi C, Haruta T. Is a reversible splenial lesion a sign of encephalopathy? Pediatr Neurol 41: 143-145 (2009) 

Tsuji M, Kinoshita M, Imai Y, Kawamoto M, Kohara N. Facioscapulohumeral muscular dystrophy presenting with hypertrophic cardiomyopathy: a case study Neuromuscul Disord 19: 140-142 (2009) 

Johnston MV, Ishida A, Ishida WN, Matsushita HB, Nishimura A, Tsuji M. Plasticity and injury in the developing brain. Brain Dev 31: 1-10 (2009)

Takanashi J, Tsuji M, Amemiya K, Tada H, Barkovich AJ. Mild influenza encephalopathy with biphasic seizures and late reduced diffusion. J Neurol Sci 256: 86-89 (2007)

Sakamoto HM, Yoshioka M, Tsuji M, Kuroki S, Higuchi Y, Nonaka I, Nishino I. A case of congenital neuromuscular disease with uniform type 1 fibers. Brain Dev 28: 202-205 (2006)

Tsuji M, Wilson MA, Lange MS, Johnston MV. Minocycline worsens hypoxic-ischemic brain injury in a neonatal mouse model. Exp Neurol 189: 58-65 (2004)

Tsuji M, Kuroki S, Maeda H, Yoshioka M, Maihara T, Fujii T, Ito M. Leigh syndrome associated with West syndrome. Brain Dev 25: 245-250 (2003)

Tsuji M, Higuchi Y, Shiraishi K, Kume T, Akaike A, Hattori H. Protective effect of aminoguanidine on hypoxic-ischemic brain damage and temporal profile of brain nitric oxide in neonatal rat. Pediatr Res 47: 79-83 (2000)

Higuchi Y, Hattori H, Tsuji M, Asato R, Nakahata T. Partial seizures in leukoencephalopathy with swelling and a discrepantly mild clinical course. Brain Dev 22: 387-389 (2000)

Hattori H, Fujii T, Nigami H, Higuchi Y, Tsuji M, Hamada Y. Co-segregation of benigh infantile convulsions and paroxysmal kinesigenic choreoathetosis. Brain Dev22: 432-435 (2000)

Hattori H, Higuchi Y, Tsuji M. Recurrent strokes after varicella. Ann Neurol 47: 136 (2000)

Tsuji M, Higuchi Y, Shiraishi K, Mitsuyoshi I, Hattori H. Congenital fiber type disproportion: severe form with marked improvement. Pediatr Neurol 21: 658-660 (1999)

Maihara T, Tsuji M, Higuchi Y, Hattori H. Benign familial neonatal convulsions followed by benign epilepsy with centrotemporal spikes in two siblings. Epilepsia 40: 110-113 (1999)

Higuchi Y, Hattori H, Kume T, Tsuji M, Akaike A, Furusho K. Increase in nitric oxide in hypoxic-ischemic neonatal rat brain and suppression by 7-nitroindazole and aminoguanidine. Eur J Pharmacol 342: 47-49 (1998)

Hattori H, Higuchi Y, Tsuji M, Inomata Y, Uemoto S, Asonuma K, Egawa H, Kiuchi T, Furusho K, Yamaoka Y, Tanaka K. Living-related liver transplantation and neurological outcome in children with fulminant hepatic failure. Transplantation 65: 686-692 (1998)

Fujii T, Hattori H, Higuchi Y, Tsuji M, Mitsuyoshi I. Phenotypic differences between TC and TG mutations at nt 8993 of mitochondrial DNA in Leigh syndrome. Pediatr Neurol 18: 275-277 (1998)